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5:25
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JAMA Network
Gene Editing Inside the Body Using CRISPR
CRISPR-Cas9 technology is used to edit DNA to correct genetic abnormalities, but until now has required cells be removed for gene editing outside the body. In March 2020 researchers announced a test of the first in-the-body (in vivo) CRISPR-Cas9 treatment for Leber congenital amaurosis (LCA) type 10, a condition that causes severe, early-onset ...
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Abhay Mishra | Academic Advisor on Instagram: "Follow🎖️What is CRISPR-Cas9? CRISPR-Cas9 is a genome-editing technology adapted from a natural defense mechanism found in bacteria. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats, and Cas9 is a DNA-cutting enzyme (endonuclease). In simple terms, CRISPR-Cas9 acts as molecular scissors guided by RNA, allowing scientists to precisely cut DNA at a chosen location in the genome. Core Components Guide RNA (gRNA): Directs Cas9
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